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Symbol
Name
ID
Hells
helicase, lymphoid specific
MGI:106209
Phenotype annotations related to hematopoietic system
Darker colors indicate more annotations
Human Phenotypes
Decreased circulating antibody level
Agammaglobulinemia
Abnormal B cell morphology
Disease(s) Associated with HELLS
immunodeficiency-centromeric instability-facial anomalies syndrome 4

Mouse Phenotypes
small thymus
thymus hypoplasia
increased double-negative T cell number
decreased granulocyte number
decreased B cell number
increased CD8-positive, alpha-beta T cell number
small spleen
decreased IgG1 level
Availability Mouse Genotype
Hellstm1a(EUCOMM)Wtsi/Hellstm1a(EUCOMM)Wtsi
Hellstm1Kmu/Hellstm1Kmu
Hellstm1Rarc/Hellstm1Rarc

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory